Linked Life Data

1646441

Source:http://linkedlifedata.com/resource/pubmed/id/1646441

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1991-7-18
pubmed:abstractText
The effect of Lipiodol (LPD) on the hepatic parenchyma bearing VX2 tumor was investigated in 12 rabbits. In these rabbits Adriamycin (ADM) soluble Urografin and LPD were injected through the hepatic artery. As the control another 12 rabbits bearing VX2 tumor which were intraarterially injected with ADM solution in saline were used. Liver function tests revealed significantly higher values of serum transaminases in the LPD group than in the control group. Histologically in the LPD group, hepatocellular degeneration was observed and the severity was at its peak 3 days after injection whereas control animals preserved almost normal structure. The degeneration of the tumor-bearing lobe was more severe than that of the tumor-free lobe. This study showed the histologically and functionally demonstrable adverse effects of LPD.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0048-0428
pubmed:author
pubmed:issnType
Print
pubmed:day
25
pubmed:volume
51
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
289-91
pubmed:dateRevised
2011-7-26
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
[Hepatic parenchymal changes after intraarterial administration of lipiodol: an animal experiment].
pubmed:affiliation
Third Department of Internal Medicine, Kansai Medical University.
pubmed:publicationType
Journal Article, English Abstract