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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1991-7-12
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pubmed:abstractText |
Plasma concentrations of corticotropin releasing hormone (CRH) and the serum concentrations of luteinizing hormone (LH), follicle stimulating hormone (FSH), testosterone, adrenocorticotropic hormone (ACTH) and cortisol were measured in seven physically active males after acute exercise on a treadmill using the Bruce protocol. Measurements were made in the basal pre-exercise state, immediately after exercise, and at 30-min intervals for 3 h after exercise. Serum LH concentrations declined following exercise reaching nadir values between 60 and 180 min after exercise (90 min post exercise in the group). The nadir values in individual volunteers were significantly lower than both the baseline and post-exercise levels. This fall in serum LH concentration appeared to follow a slight but significant elevation of the plasma concentration of CRH which reached peak levels when measured immediately post exercise. Plasma ACTH concentrations paralleled the rise in CRH, but fell to undetectable levels of below 13.8 nmol.l-1 (less than 5 ng.l-1) 60 min after exercise. Plasma cortisol concentrations peaked approximately 30 min after the rise in ACTH, after which they gradually declined to baseline levels. Plasma testosterone concentrations paralleled the concentrations of LH. The data suggest that CRH, on the basis of its previously described gonadotropin-depressant property, may be the hormone involved in the exercise-mediated decline in serum LH. Alternatively, some as yet unidentified factor(s), may be involved in producing the altered concentrations of both LH and CRH.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adrenocorticotropic Hormone,
http://linkedlifedata.com/resource/pubmed/chemical/Corticotropin-Releasing Hormone,
http://linkedlifedata.com/resource/pubmed/chemical/Gonadotropins,
http://linkedlifedata.com/resource/pubmed/chemical/Hydrocortisone,
http://linkedlifedata.com/resource/pubmed/chemical/Lactates,
http://linkedlifedata.com/resource/pubmed/chemical/Lactic Acid
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pubmed:status |
MEDLINE
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pubmed:issn |
0301-5548
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
171-4
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:1646105-Adrenocorticotropic Hormone,
pubmed-meshheading:1646105-Adult,
pubmed-meshheading:1646105-Corticotropin-Releasing Hormone,
pubmed-meshheading:1646105-Gonadotropins,
pubmed-meshheading:1646105-Heart Rate,
pubmed-meshheading:1646105-Humans,
pubmed-meshheading:1646105-Hydrocortisone,
pubmed-meshheading:1646105-Lactates,
pubmed-meshheading:1646105-Lactic Acid,
pubmed-meshheading:1646105-Male,
pubmed-meshheading:1646105-Oxygen Consumption,
pubmed-meshheading:1646105-Physical Exertion,
pubmed-meshheading:1646105-Physical Fitness,
pubmed-meshheading:1646105-Time Factors
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pubmed:year |
1991
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pubmed:articleTitle |
Corticotropin releasing hormone and gonadotropin secretion in physically active males after acute exercise.
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pubmed:affiliation |
Department of Medicine, University of California, Irvine 92717.
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pubmed:publicationType |
Journal Article
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