Linked Life Data

16459453

Source:http://linkedlifedata.com/resource/pubmed/id/16459453

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2006-2-7
pubmed:abstractText
During adolescence, little is known about the relationship between leptin and metabolic hormones and how these are modified by body composition and exercise. This study determined: 1) the relationships between leptin, triiodothyronine, cortisol, and insulin, and 2) whether these relationships were modified by body composition and exercise. Fasting hormonal concentrations were assessed from 80 girls and 80 boys, aged 11-18 yr. In a multiple regression model, including the hormones and gender, only gender and insulin were significant predictors of leptin (R2 = 0.394; p <0.001). In a second model, including body fat and exercise, the levels of body fat, gender, free triidothyronine and cortisol explained 59.6% of the variance in leptin (p <0.05). The results suggest that in adolescents, the relationship between leptin and insulin is mediated by body fat. Leptin is negatively associated with cortisol in boys and with thyroid hormones in girls; these hormones possibly interact to sustain normal growth and maturation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0334-018X
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1073-81
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
The relationship between leptin, metabolic hormones, exercise and body composition in adolescents.
pubmed:affiliation
Applied Physiology Laboratory, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-8605, USA. drubin@med.unc.edu
pubmed:publicationType
Journal Article