|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0007600,
umls-concept:C0011306,
umls-concept:C0023449,
umls-concept:C0027651,
umls-concept:C0205263,
umls-concept:C0439859,
umls-concept:C0871261,
umls-concept:C1516044,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
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|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2006-2-6
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|
pubmed:abstractText |
Several studies have demonstrated that dendritic cells (DCs) pulsed with tumor lysate or apoptotic tumor cells can elicit effective T-cell responses. This technique does not require the identification of the tumor antigen or HLA haplotype of the patient. We applied this approach to induce HLA class I- and class II-restricted T-cell responses directed against autologous acute lymphocytic leukemia (B-ALL) cell line NH-1.
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|
pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
0301-472X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
34
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
197-207
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|
pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:16459188-Apoptosis,
pubmed-meshheading:16459188-CD4-Positive T-Lymphocytes,
pubmed-meshheading:16459188-CD8-Positive T-Lymphocytes,
pubmed-meshheading:16459188-Cell Fusion,
pubmed-meshheading:16459188-Cell Line, Tumor,
pubmed-meshheading:16459188-Cytotoxicity Tests, Immunologic,
pubmed-meshheading:16459188-Dendritic Cells,
pubmed-meshheading:16459188-Epitopes,
pubmed-meshheading:16459188-Epstein-Barr Virus Nuclear Antigens,
pubmed-meshheading:16459188-Female,
pubmed-meshheading:16459188-HLA-DR Antigens,
pubmed-meshheading:16459188-Histocompatibility Antigens Class II,
pubmed-meshheading:16459188-Humans,
pubmed-meshheading:16459188-Infant,
pubmed-meshheading:16459188-Lymphocyte Activation,
pubmed-meshheading:16459188-Precursor Cell Lymphoblastic Leukemia-Lymphoma
|
|
pubmed:year |
2006
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|
pubmed:articleTitle |
Induction of autologous CD4- and CD8-mediated T-cell responses against acute lymphocytic leukemia cell line using apoptotic tumor cell-loaded dendritic cells.
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|
pubmed:affiliation |
Department of Pathology, Sapporo Medical University School of Medicine, Sapporo, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study
|
