Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1991-7-5
pubmed:databankReference
pubmed:abstractText
The 7E gene is expressed late in normal development of Dictyostelium discoideum after pseudoplasmodium formation. After disaggregation of the developing cells, transcription of this gene depends entirely on exogenous 3'5' cyclic AMP (cAMP). The 5' flanking region of the 7E gene contains two TATA box-oligo (dT) promoter motifs but analysis of 7E gene expression by primer extension shows only a single primary transcript with transcription initiating immediately after the most proximal promoter motif during development or in disaggregated cells in the presence of exogenous cAMP. Four C-rich sequences lie within 350bp upstream of the cap site, analogous to the upstream elements implicated in the cAMP regulation of several other Dictyostelium genes expressed in development.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0950-382X
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:geneSymbol
7E
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
427-32
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Sequence and expression analysis of a cAMP-responsive gene regulated during late development of Dictyostelium discoideum.
pubmed:affiliation
Department of Biochemistry and Molecular Biology, University of Leeds, UK.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't