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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2006-3-1
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pubmed:abstractText |
Manganese superoxide dismutase (MnSOD), an enzyme that catalyzes superoxide radical quenching, is hypothesized to protect against premature aging. A C47T transition in the MnSOD gene may affect the enzyme's distribution to the mitochondrion, a site of high oxidative stress. We examined the association between this polymorphism and survival.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0047-6374
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
127
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
371-7
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:16458347-Age Factors,
pubmed-meshheading:16458347-Aged,
pubmed-meshheading:16458347-Aging,
pubmed-meshheading:16458347-Antioxidants,
pubmed-meshheading:16458347-Body Mass Index,
pubmed-meshheading:16458347-Cardiovascular Diseases,
pubmed-meshheading:16458347-Catalysis,
pubmed-meshheading:16458347-Female,
pubmed-meshheading:16458347-Genotype,
pubmed-meshheading:16458347-Humans,
pubmed-meshheading:16458347-Male,
pubmed-meshheading:16458347-Middle Aged,
pubmed-meshheading:16458347-Mitochondria,
pubmed-meshheading:16458347-Neoplasms,
pubmed-meshheading:16458347-Oxidative Stress,
pubmed-meshheading:16458347-Oxygen,
pubmed-meshheading:16458347-Polymorphism, Genetic,
pubmed-meshheading:16458347-Proportional Hazards Models,
pubmed-meshheading:16458347-Risk,
pubmed-meshheading:16458347-Smoking,
pubmed-meshheading:16458347-Superoxide Dismutase,
pubmed-meshheading:16458347-Time Factors,
pubmed-meshheading:16458347-Treatment Outcome
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pubmed:year |
2006
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pubmed:articleTitle |
C47T polymorphism in manganese superoxide dismutase (MnSOD), antioxidant intake and survival.
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pubmed:affiliation |
Department of Nutrition, Harvard School of Public Health, 665 Huntington Avenue, Building 2, Boston, MA, United States.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, N.I.H., Extramural
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