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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1991-7-8
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pubmed:abstractText |
Low-frequency peripheral nerve stimulation may induce widespread cutaneous and muscular vasodilatation in animals and humans due to sympatho-inhibition. This response has in humans been shown to be associated with a lowering of the systemic vascular resistance and arterial pressure. In the present study the effectiveness of low-frequency (2 Hz) transcutaneous electrical nerve stimulation (TNS) has been examined in 46 patients, all 41-43 years of age, with a primary diagnosis of uncomplicated mild/moderate hypertension (90-115 mmHg diastolic pressure). The study was designed blind with matched controls in a TNS group and a placebo group. The blood pressure was measured objectively with an automatic monitor. In a short-term experiment TNS produced a significant lowering of systolic, mean arterial, and diastolic pressures amounting to 8 mmHg (P less than 0.01), 6 mmHg (P less than 0.01), and 4 mmHg (P less than 0.02), respectively. In a long-term study, after 2 weeks of daily stimulation, a similar depression was recorded with no stimulation on the day of examination. An eventual clinical use of the depressor effect of TNS demands further clinical research.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0144-5979
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
161-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1645634-Adult,
pubmed-meshheading:1645634-Blood Pressure,
pubmed-meshheading:1645634-Double-Blind Method,
pubmed-meshheading:1645634-Electric Stimulation,
pubmed-meshheading:1645634-Female,
pubmed-meshheading:1645634-Humans,
pubmed-meshheading:1645634-Hypertension,
pubmed-meshheading:1645634-Male,
pubmed-meshheading:1645634-Peripheral Nerves,
pubmed-meshheading:1645634-Synaptic Transmission,
pubmed-meshheading:1645634-Time Factors,
pubmed-meshheading:1645634-Transcutaneous Electric Nerve Stimulation
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pubmed:year |
1991
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pubmed:articleTitle |
Low-frequency transcutaneous nerve stimulation in mild/moderate hypertension.
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pubmed:affiliation |
Rogaland Central Hospital, Stavanger, Norway.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|