|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2006-3-24
|
|
pubmed:abstractText |
Atherosclerosis is associated with immune responses to oxidized low-density lipoprotein (oxLDL). The presence of activated macrophages and T cells in lesions suggests that cell-mediated immune reactions are taking place during the disease process. However, the role of specific immune responses has remained unclear. We have previously shown that transfer of CD4+ T cells from apolipoprotein E knockout mice (apoE(-/-)) into immunodeficient apoE(-/-) scid/scid mice accelerates disease.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adjuvants, Immunologic,
http://linkedlifedata.com/resource/pubmed/chemical/Apolipoproteins E,
http://linkedlifedata.com/resource/pubmed/chemical/Autoantigens,
http://linkedlifedata.com/resource/pubmed/chemical/Hemocyanin,
http://linkedlifedata.com/resource/pubmed/chemical/Interferon-gamma,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-5,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukins,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, LDL,
http://linkedlifedata.com/resource/pubmed/chemical/keyhole-limpet hemocyanin,
http://linkedlifedata.com/resource/pubmed/chemical/oxidized low density lipoprotein
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
1524-4636
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
26
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
864-70
|
|
pubmed:dateRevised |
2008-11-21
|
|
pubmed:meshHeading |
pubmed-meshheading:16456097-Adjuvants, Immunologic,
pubmed-meshheading:16456097-Adoptive Transfer,
pubmed-meshheading:16456097-Animals,
pubmed-meshheading:16456097-Apolipoproteins E,
pubmed-meshheading:16456097-Atherosclerosis,
pubmed-meshheading:16456097-Autoantigens,
pubmed-meshheading:16456097-CD4-Positive T-Lymphocytes,
pubmed-meshheading:16456097-Hemocyanin,
pubmed-meshheading:16456097-Immunity, Cellular,
pubmed-meshheading:16456097-Interferon-gamma,
pubmed-meshheading:16456097-Interleukin-5,
pubmed-meshheading:16456097-Interleukins,
pubmed-meshheading:16456097-Lipoproteins, LDL,
pubmed-meshheading:16456097-Mice,
pubmed-meshheading:16456097-Mice, Inbred C57BL,
pubmed-meshheading:16456097-Mice, Knockout,
pubmed-meshheading:16456097-Mice, SCID,
pubmed-meshheading:16456097-Th1 Cells
|
|
pubmed:year |
2006
|
|
pubmed:articleTitle |
Adoptive transfer of CD4+ T cells reactive to modified low-density lipoprotein aggravates atherosclerosis.
|
|
pubmed:affiliation |
Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, Stockholm, Sweden. Xinghua.Zhou@ki.se
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
