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PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1991-7-10
pubmed:abstractText
Antigen expression by human small cell lung carcinoma cells in serous effusions was determined by staining smears of cells with a panel of four monoclonal antibodies including UJ13A (cluster 1 antigen) and CAM 5.2 (anti-cytokeratin) using an immunoalkaline phosphatase technique. This was quantified by counting the proportion of stained and unstained tumour cells and was compared with that of small cell lung carcinoma in sections of solid tumour. Differential expression of antigen expression was noted with significantly fewer small cell carcinoma cells in serous effusions staining with UJ13A or CAM 5.2. The reasons for this differential expression are unknown, but may reflect adaptation to a different environment or be a prerequisite for spread to serous space.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0306-9443
pubmed:author
pubmed:issnType
Print
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
54-5
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Differential expression of antigens by human small cell lung carcinoma in sections of tumour and in serous effusions.
pubmed:affiliation
Chest and Allergy Clinic, St Mary's Hospital, London, UK.
pubmed:publicationType
Journal Article, Comparative Study