Source:http://linkedlifedata.com/resource/pubmed/id/16455454
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
2006-2-3
|
| pubmed:abstractText |
Surgical resection continues to offer the only hope for cure of colorectal cancer metastatic to the liver. Tumor involvement of the vena cava is often viewed as a contraindication to surgical resection. Whereas proven technically feasible, the survival advantages of en bloc liver and vena cava resection remain unclear. We reviewed all patients at a tertiary care center who had resection of colorectal liver metastases, including those with vena cava resections. Eleven patients had en bloc liver and vena cava resection between 1988 and 2002; during the same time period, 97 patients underwent isolated liver resection. There were no perioperative deaths in the 11 patients. All resections had negative histological margins. Mean follow-up was 33 months from the date of surgery. Median disease-free survival of the group having caval resections was 9 months, whereas median survival was 34 months. When compared to the cohort of isolated hepatic resections, the group undergoing caval resections experienced a significantly reduced disease-free survival of 18.6 vs. 9.1 months, respectively (P = 0.03); however, there was no difference in overall survival between the two groups at 55.2 vs. 34.3 months, respectively (P = 0.20). Colorectal liver metastases involving the vena cava should be considered for surgical resection.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
1091-255X
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
10
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
220-6
|
| pubmed:dateRevised |
2006-11-15
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| pubmed:meshHeading |
pubmed-meshheading:16455454-Adult,
pubmed-meshheading:16455454-Aged,
pubmed-meshheading:16455454-Blood Vessel Prosthesis Implantation,
pubmed-meshheading:16455454-Cohort Studies,
pubmed-meshheading:16455454-Colorectal Neoplasms,
pubmed-meshheading:16455454-Disease-Free Survival,
pubmed-meshheading:16455454-Female,
pubmed-meshheading:16455454-Follow-Up Studies,
pubmed-meshheading:16455454-Hepatectomy,
pubmed-meshheading:16455454-Humans,
pubmed-meshheading:16455454-Liver Neoplasms,
pubmed-meshheading:16455454-Male,
pubmed-meshheading:16455454-Middle Aged,
pubmed-meshheading:16455454-Neoplasm Recurrence, Local,
pubmed-meshheading:16455454-Retrospective Studies,
pubmed-meshheading:16455454-Survival Rate,
pubmed-meshheading:16455454-Time Factors,
pubmed-meshheading:16455454-Vena Cava, Inferior
|
| pubmed:year |
2006
|
| pubmed:articleTitle |
Combined hepatic and inferior vena cava resection for colorectal metastases.
|
| pubmed:affiliation |
Department of Surgery, Section of Hepatobiliary Surgery, University of Alberta, Walter Mackenzie Health Sciences Centre, 8440-112 Street, Edmonton, Alberta, Canada T6G 2B7.
|
| pubmed:publicationType |
Journal Article,
Comparative Study
|