Source:http://linkedlifedata.com/resource/pubmed/id/16455233
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2006-2-20
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pubmed:abstractText |
Forty-three Shigella sonnei isolates from adult patients with diarrhoea in Dakar were analysed for the presence of integrons. Isolates were resistant to sulphamethoxazole, trimethoprim, tetracycline, streptomycin and spectinomycin. A high prevalence of class 2 integrons (93%) was found. These integrons showed three distinct structures: a class 2 integron, part of the Tn7 family and its derivatives, carrying four cassettes in the order dfrA1-sat-aadA1-orfX; a truncated class 2 integron, without orfX; and a third type ca. 4 kb in size. These class 2 integrons probably play a role in the spread of multiresistance in S. sonnei isolates. To our knowledge, this is the first description of class 2 integrons in S. sonnei isolated in sub-Saharan Africa.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0924-8579
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
267-70
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pubmed:meshHeading |
pubmed-meshheading:16455233-Adult,
pubmed-meshheading:16455233-Anti-Bacterial Agents,
pubmed-meshheading:16455233-Diarrhea,
pubmed-meshheading:16455233-Drug Resistance, Bacterial,
pubmed-meshheading:16455233-Humans,
pubmed-meshheading:16455233-Integrons,
pubmed-meshheading:16455233-Prevalence,
pubmed-meshheading:16455233-Senegal,
pubmed-meshheading:16455233-Shigella sonnei
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pubmed:year |
2006
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pubmed:articleTitle |
Class 2 integron-associated antibiotic resistance in Shigella sonnei isolates in Dakar, Senegal.
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pubmed:affiliation |
Laboratoire de Bactériologie Expérimentale, Institut Pasteur, BP 220, Dakar, Sénégal. gassama@pasteur.sn
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pubmed:publicationType |
Journal Article
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