Source:http://linkedlifedata.com/resource/pubmed/id/16455106
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2006-6-8
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pubmed:abstractText |
Epidemiological, clinical, and experimental studies have linked low or lowered cholesterol levels to aggressive behavior. However, no study has measured the relationship between aggression and apolipoprotein A-I/apolipoprotein B ratio, a robust indicator of cardiac risk. Plasma levels of total cholesterol, HDL-C, LDL-C, triglycerides, apolipoprotein A-I, and apolipoprotein B were measured and correlated with Aggression Questionnaire ratings in 20 young adult males with personality disorders and/or a high propensity toward aggressive behavior and in 40 control subjects. Compared with the control subjects, the subjects in the aggressive group had lower levels of apo A-I and a lower apo A-I/apo B ratio. Whereas in the control subjects, higher levels of aggression were correlated with lower levels of atherogenic lipoproteins (LDL-C and apo B), in the aggressive subjects higher levels of aggression were correlated with lower levels of anti-atherogenic lipoproteins (HDL-C and apo A-I) and higher levels of LDL-C. The results of this study confirm the existence of a relationship between blood lipids and aggressive behavior in young adult males and suggest that the apo A-I/apo B ratio might be an additional marker in the search for biological correlates of increased risk of violence.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0022-3956
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
466-72
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16455106-Adult,
pubmed-meshheading:16455106-Aggression,
pubmed-meshheading:16455106-Apolipoprotein A-I,
pubmed-meshheading:16455106-Apolipoproteins B,
pubmed-meshheading:16455106-Humans,
pubmed-meshheading:16455106-Italy,
pubmed-meshheading:16455106-Lipoproteins,
pubmed-meshheading:16455106-Male,
pubmed-meshheading:16455106-Reference Values,
pubmed-meshheading:16455106-Triglycerides,
pubmed-meshheading:16455106-Violence
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pubmed:year |
2006
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pubmed:articleTitle |
Apolipoprotein A-I/apolipoprotein B ratio and aggression in violent and nonviolent young adult males.
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pubmed:affiliation |
Department of Neurosciences, University of Rome Tor Vergata, via Guattani 14, 00161 Rome, Italy. alfonso.troisi@uniroma2.it
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pubmed:publicationType |
Journal Article,
Comparative Study
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