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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2006-2-1
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pubmed:abstractText |
The retina is the neurosensorial tissue of the eye and is extremely rich in polyunsaturated lipid membranes. This feature makes it especially sensitive to oxygen and/or nitrogen activated species and lipid peroxidation. Several authors have postulated the importance of superoxide (O2-) and peroxynitrite production in the development of diabetic complications. In the present study, we have used two different antioxidants, ebselen and lutein, that present as a common feature their peroxynitrite scavenging capacity, to ameliorate the oxidative stress that exists in the retina in diabetic patients.
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pubmed:language |
spa
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0365-6691
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
81
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
27-32
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16450258-Animals,
pubmed-meshheading:16450258-Antioxidants,
pubmed-meshheading:16450258-Diabetes Mellitus, Experimental,
pubmed-meshheading:16450258-Diabetic Retinopathy,
pubmed-meshheading:16450258-Disease Models, Animal,
pubmed-meshheading:16450258-Electroretinography,
pubmed-meshheading:16450258-Free Radical Scavengers,
pubmed-meshheading:16450258-Glutathione,
pubmed-meshheading:16450258-Malondialdehyde,
pubmed-meshheading:16450258-Mice,
pubmed-meshheading:16450258-Oxidative Stress,
pubmed-meshheading:16450258-Peroxynitrous Acid
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pubmed:year |
2006
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pubmed:articleTitle |
[Oxidative stress in a model of experimental diabetic retinopathy: the utility of peroxinytrite scavengers].
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pubmed:affiliation |
Universidad Cardenal Herrera-CEU, Fundación Oftalmológica del Mediterráneo, Spain.
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pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
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