Source:http://linkedlifedata.com/resource/pubmed/id/16447201
Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
2006-2-7
|
| pubmed:abstractText |
To overcome the barrier of size match, right lobe graft has been widely used in living donor liver transplantation (LDLT). We assessed donor outcome, with a focus on remnant liver volume (RLV) after right hepatectomy based on the experiences of 2 LDLT centers, as a means of guiding the establishment of safe RLV limits for donor right hepatectomy. Between January 2002 and December 2003, a consecutive 146 liver donors who underwent right hepatectomy with at least 12 months of follow-up were enrolled in this study. Donors were grouped into 2 groups according to RLV: group 1 (n = 74), <35% (range, 26.9-34.9) and group 2 (n = 72), > or = 35% (35.0-46.8). No donors died or suffered a life-threatening complication. Mean peak serum postoperative aspartate aminotransferase (AST) and alanine aminotransferase (ALT) (IU/L) levels were 219.5 +/- 79.9 and 231.5 +/- 83.3 in group 1 and 210.3 +/- 81.6 and 225.8 +/- 93.0 in group 2 (P = 0.497 and 0.699), respectively. Mean peak serum total bilirubin (TB) (mg/dL) level in group 1 (3.4 +/- 1.6) was higher than in group 2 (2.8 +/- 1.4; P = 0.023). Overall 23 (15.8%) major morbidities, 10 in group 1 (13.5%) and 13 in group 2 (18.1%), occurred according to Clavien's system (P = 0.939). These included bleeding (n = 3 in group 1 and n = 6 in group 2; P = 0.282), ileus (n = 3 and 1; P = 0.324), biliary leakage (n = 4 and 4; P = 0.968), and pneumonia (n = 0 and 2; P = 0.149). Minor morbidities were also comparable in the 2 groups. In conclusion, the outcome of donors with an RLV of <35% was not different from that of donors with an RLV of > or = 35%, with the exception of transient cholestasis. Therefore, a remnant RLV of <35% does not appear to be a contraindication for right liver procurement in living donors.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
1527-6465
|
| pubmed:author | |
| pubmed:copyrightInfo |
Copyright 2006 AASLD
|
| pubmed:issnType |
Print
|
| pubmed:volume |
12
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
201-6
|
| pubmed:meshHeading |
pubmed-meshheading:16447201-Adolescent,
pubmed-meshheading:16447201-Adult,
pubmed-meshheading:16447201-Age Distribution,
pubmed-meshheading:16447201-Cohort Studies,
pubmed-meshheading:16447201-Female,
pubmed-meshheading:16447201-Follow-Up Studies,
pubmed-meshheading:16447201-Graft Rejection,
pubmed-meshheading:16447201-Hepatectomy,
pubmed-meshheading:16447201-Humans,
pubmed-meshheading:16447201-Incidence,
pubmed-meshheading:16447201-Liver Function Tests,
pubmed-meshheading:16447201-Liver Regeneration,
pubmed-meshheading:16447201-Liver Transplantation,
pubmed-meshheading:16447201-Living Donors,
pubmed-meshheading:16447201-Male,
pubmed-meshheading:16447201-Middle Aged,
pubmed-meshheading:16447201-Organ Preservation,
pubmed-meshheading:16447201-Organ Size,
pubmed-meshheading:16447201-Postoperative Complications,
pubmed-meshheading:16447201-Probability,
pubmed-meshheading:16447201-Risk Assessment,
pubmed-meshheading:16447201-Sex Distribution
|
| pubmed:year |
2006
|
| pubmed:articleTitle |
Outcome of donors with a remnant liver volume of less than 35% after right hepatectomy.
|
| pubmed:affiliation |
Department of Surgery, Seoul National University College of Medicine, Chongno-gu, Seoul, Korea.
|
| pubmed:publicationType |
Journal Article
|