Source:http://linkedlifedata.com/resource/pubmed/id/16447060
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2006-2-21
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pubmed:abstractText |
The SMXA-5 mouse is one of the SMXA recombinant inbred substrains established from the non-diabetic SM/J and A/J strains, and is a model for polygenic type 2 diabetes, characterised by moderately impaired glucose tolerance and hyperinsulinaemia. These diabetic traits are worsened by feeding a high-fat diet. The aim of this study was to dissect the diabetogenic loci in the A/J regions of the SMXA-5 genome that contribute to diabetes-related traits.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0012-186X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
486-95
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pubmed:meshHeading |
pubmed-meshheading:16447060-Animals,
pubmed-meshheading:16447060-Blood Glucose,
pubmed-meshheading:16447060-Body Mass Index,
pubmed-meshheading:16447060-Chromosomes, Mammalian,
pubmed-meshheading:16447060-Diabetes Mellitus,
pubmed-meshheading:16447060-Female,
pubmed-meshheading:16447060-Glucose Tolerance Test,
pubmed-meshheading:16447060-Humans,
pubmed-meshheading:16447060-Male,
pubmed-meshheading:16447060-Mice,
pubmed-meshheading:16447060-Mice, Inbred Strains,
pubmed-meshheading:16447060-Obesity,
pubmed-meshheading:16447060-Phenotype,
pubmed-meshheading:16447060-Quantitative Trait Loci
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pubmed:year |
2006
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pubmed:articleTitle |
Major quantitative trait locus on chromosome 2 for glucose tolerance in diabetic SMXA-5 mouse established from non-diabetic SM/J and A/J strains.
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pubmed:affiliation |
Department of Applied Molecular Bioscience, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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