Source:http://linkedlifedata.com/resource/pubmed/id/16444677
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2007-7-19
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pubmed:abstractText |
This report documents the clinical activity of caspofungin in a 13-year-old girl with acute myeloid leukemia (AML) and chronic disseminated candidiasis (CDC), refractory to amphotericin B and fluconazole. Caspofungin was started at 50 mg/d resulting in a temporary response. With no further clinical improvement and radiological progress after 2 months of therapy, the dose of caspofungin was increased to 100 mg/d, leading to a sustained clinical response. Therapy was given for a total of 12 months and had no attributable adverse effects. This approach resulted in successful treatment of refractory CDC with caspofungin.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
1545-5009
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pubmed:author | |
pubmed:copyrightInfo |
Copyright (c) 2006 Wiley-Liss, Inc.
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pubmed:issnType |
Print
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
360-2
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pubmed:dateRevised |
2009-1-12
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pubmed:meshHeading |
pubmed-meshheading:16444677-Adolescent,
pubmed-meshheading:16444677-Antifungal Agents,
pubmed-meshheading:16444677-Candidiasis,
pubmed-meshheading:16444677-Chronic Disease,
pubmed-meshheading:16444677-Echinocandins,
pubmed-meshheading:16444677-Female,
pubmed-meshheading:16444677-Humans,
pubmed-meshheading:16444677-Immunocompromised Host,
pubmed-meshheading:16444677-Leukemia, Myeloid,
pubmed-meshheading:16444677-Liver Diseases,
pubmed-meshheading:16444677-Magnetic Resonance Imaging,
pubmed-meshheading:16444677-Peptides, Cyclic,
pubmed-meshheading:16444677-Splenic Diseases
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pubmed:year |
2007
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pubmed:articleTitle |
Successful treatment of refractory chronic disseminated candidiasis after prolonged administration of caspofungin in a child with acute myeloid leukemia.
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pubmed:affiliation |
Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology, University of Freiburg, Freiburg, Germany. kontny@kikli.ukl.uni-freiburg.de
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pubmed:publicationType |
Journal Article,
Case Reports
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