Linked Life Data

16444163

Source:http://linkedlifedata.com/resource/pubmed/id/16444163

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2006-1-30
pubmed:abstractText
The incidence of thyroid cancer in childhood amounts to approximately 0,5/100.000/year. However, after exposure to ionizing irradiation, the incidence may increase more than 20 fold. In children, lymph node metastases of differentiated thyroid cancer are frequent (more than 50%); distant metastases mainly to the lung are seen in 20-30%. The method of choice for the primary diagnosis of thyroid cancer today is ultrasonography with 7,5 - 10 MHz probes, accompanied by fine-needle aspiration biopsy. Differentiated thyroid cancer has to be treated with a multidisciplinary approach comprising total thyroidectomy and lymph node dissection, post-operative radioiodine treatment and TSH-suppression by levothyroxine. The long-term results of this treatment approach are generally good with 10-year survival rates of 95% and higher. The treatment of children with disseminated pulmonary metastases however, may be complicated due to the increased risk of the induction of pulmonary fibrosis by radioiodine.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1565-4753
pubmed:author
pubmed:issnType
Print
pubmed:volume
1 Suppl 2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
230-5; discussion 235-6
pubmed:dateRevised
2008-4-9
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Differentiated thyroid cancer in childhood: pathology, diagnosis, therapy.
pubmed:affiliation
Clinic and Policlinic for Nuclear Medicine, University of Würzburg. reiners@nuklearmedizin.uni-wuerzburg.de
pubmed:publicationType
Journal Article, Review