Source:http://linkedlifedata.com/resource/pubmed/id/16442391
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
2006-1-30
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| pubmed:abstractText |
Many studies have shown that ST-segment depression is a strong predictor of poor outcomes in patients with non-ST-segment elevation acute coronary syndromes (NSTE-ACSs); however, lead aVR was not considered in these studies. The present study examined the prognostic usefulness of the 12-lead electrocardiogram in combination with biochemical markers in 333 patients with NSTE-ACS. ST-segment deviation of > or =0.5 mm was considered clinically significant. Coronary angiography was performed a median of 3 days after admission in all patients. The primary end point was the composite of death, myocardial infarction, and urgent revascularization at 90 days. ST-segment elevation in lead aVR (odds ratio 13.8, 95% confidence interval 1.43 to 100.9, p = 0.03) and increased troponin T (odds ratio 7.9, 95% confidence interval 1.22 to 123.8, p = 0.04) were the only independent predictors of restricted events (death or myocardial infarction) at 90 days. ST-segment elevation in lead aVR (odds ratio 12.8, 95% confidence interval 4.80 to 33.9, p < 0.0001) and increased troponin T (odds ratio 2.03, 95% confidence interval 1.20 to 4.29, p = 0.04) were also the only independent predictors of adverse events (death, myocardial infarction, or urgent revascularization) at 90 days. When ST-segment status in lead aVR was combined with troponin T, patients with ST-segment elevation in lead aVR and increased troponin T had the highest rates of left main or 3-vessel coronary disease (62%) and 90-day adverse outcomes (47%). In conclusion, our findings suggest that ST-segment status in lead aVR combined with troponin T on admission is a simple and useful clinical tool for early risk stratification in patients with NSTE-ACS.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
AIM
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| pubmed:chemical | |
| pubmed:status |
MEDLINE
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| pubmed:month |
Feb
|
| pubmed:issn |
0002-9149
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| pubmed:author |
pubmed-author:EbinaToshiakiT,
pubmed-author:HibiKiyoshiK,
pubmed-author:IshikawaToshiyukiT,
pubmed-author:IwahashiNoriakiN,
pubmed-author:KannaMasahikoM,
pubmed-author:KimuraKazuoK,
pubmed-author:KosugeMasamiM,
pubmed-author:KusamaIkuyoshiI,
pubmed-author:NozawaNaokiN,
pubmed-author:OkudaJyunJ,
pubmed-author:OzakiHiroyukiH,
pubmed-author:TsukaharaKengoK,
pubmed-author:UmemuraSatoshiS,
pubmed-author:YanoHidetoH
|
| pubmed:issnType |
Print
|
| pubmed:day |
1
|
| pubmed:volume |
97
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
334-9
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| pubmed:meshHeading |
pubmed-meshheading:16442391-Aged,
pubmed-meshheading:16442391-Aged, 80 and over,
pubmed-meshheading:16442391-Angina, Unstable,
pubmed-meshheading:16442391-Biological Markers,
pubmed-meshheading:16442391-Coronary Angiography,
pubmed-meshheading:16442391-Electrocardiography,
pubmed-meshheading:16442391-Female,
pubmed-meshheading:16442391-Humans,
pubmed-meshheading:16442391-Male,
pubmed-meshheading:16442391-Middle Aged,
pubmed-meshheading:16442391-Myocardial Infarction,
pubmed-meshheading:16442391-Prognosis,
pubmed-meshheading:16442391-Risk Assessment,
pubmed-meshheading:16442391-Troponin T
|
| pubmed:year |
2006
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| pubmed:articleTitle |
Combined prognostic utility of ST segment in lead aVR and troponin T on admission in non-ST-segment elevation acute coronary syndromes.
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| pubmed:affiliation |
The Division of Cardiology, Yokohama City University Medical Center, Yokohama, Japan.
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| pubmed:publicationType |
Journal Article
|