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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2006-1-26
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pubmed:abstractText |
Xenotransplantation may provide a solution to the increasing shortage of donor organs. Acute vascular rejection and cell-mediated rejection remain the primary barriers to successful xenotransplantation. In animal models where acute vascular rejection can be attenuated, xenografts succumb to cell-mediated rejection. The mechanisms of acute vascular rejection and cell-mediated rejection are poorly understood.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0041-1337
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
27
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pubmed:volume |
81
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
265-72
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16436971-Animals,
pubmed-meshheading:16436971-Antibodies, Heterophile,
pubmed-meshheading:16436971-B-Lymphocytes,
pubmed-meshheading:16436971-Base Sequence,
pubmed-meshheading:16436971-CD4-Positive T-Lymphocytes,
pubmed-meshheading:16436971-DNA, Complementary,
pubmed-meshheading:16436971-Graft Rejection,
pubmed-meshheading:16436971-Heart Transplantation,
pubmed-meshheading:16436971-Humans,
pubmed-meshheading:16436971-Immune Tolerance,
pubmed-meshheading:16436971-Interleukin-12,
pubmed-meshheading:16436971-Interleukin-12 Subunit p40,
pubmed-meshheading:16436971-Lymphocyte Activation,
pubmed-meshheading:16436971-Mice,
pubmed-meshheading:16436971-Mice, Inbred C3H,
pubmed-meshheading:16436971-Mice, Inbred C57BL,
pubmed-meshheading:16436971-Mice, Knockout,
pubmed-meshheading:16436971-Protein Subunits,
pubmed-meshheading:16436971-Rats,
pubmed-meshheading:16436971-Rats, Inbred Lew,
pubmed-meshheading:16436971-Transplantation, Heterologous,
pubmed-meshheading:16436971-Transplantation, Homologous
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pubmed:year |
2006
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pubmed:articleTitle |
Regulation of B- and T-cell mediated xenogeneic transplant rejection by interleukin 12.
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pubmed:affiliation |
Division of Experimental Therapeutics, University Health Network, Toronto General Research Institute, Toronto, Ontario, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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