Linked Life Data

16436597

Source:http://linkedlifedata.com/resource/pubmed/id/16436597

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2006-1-26
pubmed:abstractText
Neuronal activity in posterior cingulate cortex (CGp) is modulated by visual stimulation, saccades, and eye position, suggesting a role for this area in visuospatial transformations. The goal of this study was to determine whether neuronal responses in CGp are anchored to the eyes, head, or outside the body (allocentrically). To discriminate retinocentric from nonretinocentric spatial referencing, the activity of single CGp neurons was recorded while monkeys (Macaca mulatta) performed delayed-saccade trials initiated randomly from three different starting positions to a linear array of targets passing through the neuronal response field. For most neurons, tuning curves, segregated by fixation point, aligned more closely when plotted with respect to the display than when plotted with respect to the eye, suggesting a nonretinocentric frame of reference. A second experiment differentiated between spatial referencing in coordinates anchored to the head or body and allocentric spatial referencing. Monkeys shifted gaze from a central fixation point to the array of previously used targets both before and after whole-body rotation with respect to the display. For most neurons, tuning curves, segregated by fixation position, aligned more closely when plotted as a function of target position in the room than when plotted as a function of target position with respect to the monkey. These data indicate that a population of CGp neurons encodes visuospatial events in allocentric coordinates.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1529-2401
pubmed:author
pubmed:issnType
Electronic
pubmed:day
25
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1117-27
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Allocentric spatial referencing of neuronal activity in macaque posterior cingulate cortex.
pubmed:affiliation
Department of Neurobiology, Duke University Medical Center, Durham, North Carolina 27710, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural