Linked Life Data

16435311

Source:http://linkedlifedata.com/resource/pubmed/id/16435311

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2006-3-6
pubmed:abstractText
"Loss of function" experiments have been the mainstay approach in studies seeking to determine functional roles of various brain regions in learning and memory. The hippocampal formation consists of several distinct regions that are thought to play different, yet interrelated, roles in the memory processes. Ionizing radiation offers a selective and highly flexible, relatively uninvasive method to further advance such studies. Focused applications of the radiation beam to the head under general anesthesia can selectively reduce ongoing adult neurogenesis in the dentate gyrus without causing any detectable damage to mature neurons. Further refinements of the methodology should offer many opportunities to extend our present knowledge of how and when adult neurogenesis plays a role in learning and memory.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1050-9631
pubmed:author
pubmed:copyrightInfo
(c) 2006 Wiley-Liss, Inc.
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
261-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Irradiation as an experimental tool in studies of adult neurogenesis.
pubmed:affiliation
Department of Physiology, University of Toronto, Toronto, Ontario, Canada. martin.wojowicz@utoronto.ca
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't