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rdf:type |
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lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0019564,
umls-concept:C0022116,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0185117,
umls-concept:C0205263,
umls-concept:C0205374,
umls-concept:C1413430,
umls-concept:C2348867,
umls-concept:C2911684
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pubmed:issue |
1
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pubmed:dateCreated |
2006-2-22
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pubmed:abstractText |
CITED2 is implicated in the modulating the activity of HIF-1 which is a major transcription factor involved in ischemia-related gene expression. Following transient forebrain ischemia, we found that CITED2 was induced in a subset of brain regions including dentate gyrus of the hippocampal formation and piriform cortex. Because CITED2 was not induced in cultured neurons exposed to oxygen-glucose deprivation, we concluded that hypoxia is not sufficient to trigger its induction.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0006-8993
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
9
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pubmed:volume |
1072
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
15-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16434029-Animals,
pubmed-meshheading:16434029-Brain,
pubmed-meshheading:16434029-Cyclic AMP Response Element-Binding Protein,
pubmed-meshheading:16434029-DNA Primers,
pubmed-meshheading:16434029-Hippocampus,
pubmed-meshheading:16434029-Hypoxia-Inducible Factor 1,
pubmed-meshheading:16434029-Ischemic Attack, Transient,
pubmed-meshheading:16434029-Polymerase Chain Reaction,
pubmed-meshheading:16434029-Rats,
pubmed-meshheading:16434029-Repressor Proteins,
pubmed-meshheading:16434029-Trans-Activators,
pubmed-meshheading:16434029-Transcription, Genetic
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pubmed:year |
2006
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pubmed:articleTitle |
Induction of CITED2 expression in the rat hippocampus following transient global ischemia.
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pubmed:affiliation |
Department of Anatomy and Division of Brain Korea 21 Biomedical Science, College of Medicine, Korea University, 126-1 Anam-Dong, Sungbuk-Gu, Seoul, South Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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