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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2006-1-25
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pubmed:abstractText |
Secreted phosphoprotein 1 (SPP1) is a cytokine with pleiotrophic immunological activities, including activation of macrophage chemotaxis and T-helper type 1 (Th1) immune responses. SPP1 gene polymorphisms have been shown to be associated with several immune inflammatory diseases including multiple sclerosis (MS), which is characterized by fewer allergic symptoms and lower numbers of allergen sensitizations.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0954-7894
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
36
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
219-25
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:16433860-Adult,
pubmed-meshheading:16433860-Asthma,
pubmed-meshheading:16433860-Case-Control Studies,
pubmed-meshheading:16433860-Chi-Square Distribution,
pubmed-meshheading:16433860-Exons,
pubmed-meshheading:16433860-Female,
pubmed-meshheading:16433860-Genetic Markers,
pubmed-meshheading:16433860-Genotype,
pubmed-meshheading:16433860-Homozygote,
pubmed-meshheading:16433860-Humans,
pubmed-meshheading:16433860-Hypersensitivity,
pubmed-meshheading:16433860-Immunoglobulin E,
pubmed-meshheading:16433860-Japan,
pubmed-meshheading:16433860-Lupus Erythematosus, Systemic,
pubmed-meshheading:16433860-Male,
pubmed-meshheading:16433860-Middle Aged,
pubmed-meshheading:16433860-Multiple Sclerosis,
pubmed-meshheading:16433860-Osteopontin,
pubmed-meshheading:16433860-Polymorphism, Genetic,
pubmed-meshheading:16433860-Promoter Regions, Genetic,
pubmed-meshheading:16433860-Risk Factors,
pubmed-meshheading:16433860-Sialoglycoproteins
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pubmed:year |
2006
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pubmed:articleTitle |
Sequence variants of the secreted phosphoprotein 1 gene are associated with total serum immunoglobulin E levels in a Japanese population.
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pubmed:affiliation |
First Department of Medicine, Hokkaido University School of Medicine, Sapporo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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