Linked Life Data

16429269

Source:http://linkedlifedata.com/resource/pubmed/id/16429269

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2006-2-9
pubmed:abstractText
The optic tectum differentiates from the mesencephalic alar plate and matures into a characteristically laminated structure. Evidence presented here suggests a role for Pax7 in all stages of development of tectal architecture, from regionalisation to specification of neurons and tectal topography. Analysis of Pax7 expression profiles over a range of developmental stages (E2-E12) suggests a biphasic role for Pax7: initially Pax7 expressing cells in the proliferative neuroepithelial layer establish tectal polarity whereas later Pax7 is expressed in neurons of the retino-recipient precursor stratum griseum et fibrosum superficiale (sgfs) laminae where graded levels may establish tectal topography. Furthermore, co-localisation immunofluorescence confirmed that Pax7 is initially expressed in the majority of proliferative neuroepithelial cells and later in a subset of neurons of the sgfs laminae.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
1432-1106
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
169
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
266-71
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
A multiphasic role for Pax7 in tectal development.
pubmed:affiliation
School of Animal Biology, University of Western Australia, Crawley, WA, Australia.
pubmed:publicationType
Journal Article