Source:http://linkedlifedata.com/resource/pubmed/id/16427892
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2006-1-23
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pubmed:abstractText |
Pseudoxanthoma elasticum-like diffuse elastic tissue defects and hypercoagulability are two well-established features in beta-thalassemia, which play a key role in the development of a spectrum of collateral complications in these patients. We present here a middle-aged thalassemia intermedia patient with severe aortic stenosis caused by heavy calcification of the valve, a hallmark of pseudoxanthoma elasticum. The patient underwent a successful replacement of the valve, which is the first such operation ever reported in these patients. However, rapid thrombosis leaded to failure of the mechanical valve, despite proper antithrombotic therapy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1552-6259
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
81
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
737-9
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pubmed:meshHeading |
pubmed-meshheading:16427892-Aortic Valve Stenosis,
pubmed-meshheading:16427892-Fatal Outcome,
pubmed-meshheading:16427892-Female,
pubmed-meshheading:16427892-Heart Valve Prosthesis Implantation,
pubmed-meshheading:16427892-Humans,
pubmed-meshheading:16427892-Middle Aged,
pubmed-meshheading:16427892-Prosthesis Failure,
pubmed-meshheading:16427892-Pseudoxanthoma Elasticum,
pubmed-meshheading:16427892-Thrombosis,
pubmed-meshheading:16427892-beta-Thalassemia
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pubmed:year |
2006
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pubmed:articleTitle |
Aortic valve replacement in a patient with thalassemia intermedia.
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pubmed:affiliation |
First Department of Internal Medicine, University of Athens Medical School, Laiko Hospital, Athens, Greece. dfarm1@panafonet.gr
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pubmed:publicationType |
Journal Article,
Case Reports
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