Linked Life Data

16422145

Source:http://linkedlifedata.com/resource/pubmed/id/16422145

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2006-1-20
pubmed:abstractText
The purpose of this study was to evaluate the viability of ex vivo pig eyes as a replacement model for in vivo testing in the establishment of laser eye safety standards. Previous studies of pulsed energy absorption at 3.8 microm were performed using rhesus monkey cornea at pulse durations two orders of magnitude shorter than the 8-micros pulses used in the current study. Ex vivo pig eyes were exposed to laser pulses of various energies and then evaluated to establish the statistical threshold for corneal damage. Tissue analysis (histologic evaluation) was used to determine the extent of damage to the cornea. These results can be used in the establishment of safety standards for laser use; our findings also suggest that ex vivo pig eyes are suitable models for this purpose.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1532-0820
pubmed:author
pubmed:issnType
Print
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
503-9
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
The ex vivo pig eye as a replacement model for laser safety testing.
pubmed:affiliation
Uniformed Services University of the Health Sciences, Department of Preventive Medicine and Biometrics, Bethesda, Maryland, USA.
pubmed:publicationType
Journal Article, Evaluation Studies