Linked Life Data

16421562

Source:http://linkedlifedata.com/resource/pubmed/id/16421562

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7074
pubmed:dateCreated
2006-1-19
pubmed:abstractText
The phytohormone abscisic acid (ABA) regulates various physiological processes in plants. The molecular mechanisms by which this is achieved are not fully understood. Genetic approaches have characterized several downstream components of ABA signalling, but a receptor for ABA has remained elusive. Although studies indicate that several ABA response genes encode RNA-binding or RNA-processing proteins, none has been found to be functional in binding ABA. Here we show that FCA, an RNA-binding protein involved in flowering, binds ABA with high affinity in an interaction that is stereospecific and follows receptor kinetics. The interaction between FCA and ABA has molecular effects on downstream events in the autonomous floral pathway and, consequently, on the ability of the plant to undergo transition to flowering. We further show that ABA binding exerts a direct control on the FCA-mediated processing of precursor messenger RNA. Our results indicate that FCA is an ABA receptor involved in RNA metabolism and in controlling flowering time.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1476-4687
pubmed:author
pubmed:issnType
Electronic
pubmed:day
19
pubmed:volume
439
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
290-4
pubmed:dateRevised
2008-12-30
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
The RNA-binding protein FCA is an abscisic acid receptor.
pubmed:affiliation
Department of Plant Science, University of Manitoba, Winnipeg, Manitoba R3T 2N2, Canada.
pubmed:publicationType
Journal Article, Retracted Publication, Research Support, Non-U.S. Gov't