Source:http://linkedlifedata.com/resource/pubmed/id/16421520
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2006-2-22
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pubmed:abstractText |
Downstream of mitogen-activated protein kinases (MAPKs), three structurally related MAPK-activated protein kinases (MAPKAPKs or MKs) - MK2, MK3 and MK5 - signal to diverse cellular targets. Although there is no known common function for all three MKs, these kinases are involved in important processes: MKs regulate gene expression at the transcriptional and post-transcriptional level, control cytoskeletal architecture and cell-cycle progression, and are implicated in inflammation and cancer.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1471-0072
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
120-30
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:16421520-14-3-3 Proteins,
pubmed-meshheading:16421520-Amino Acid Motifs,
pubmed-meshheading:16421520-Animals,
pubmed-meshheading:16421520-Inflammation,
pubmed-meshheading:16421520-Mice,
pubmed-meshheading:16421520-Mitogen-Activated Protein Kinase Kinases,
pubmed-meshheading:16421520-Phosphorylation,
pubmed-meshheading:16421520-Protein Conformation,
pubmed-meshheading:16421520-Transcription, Genetic
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pubmed:year |
2006
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pubmed:articleTitle |
MAPKAP kinases - MKs - two's company, three's a crowd.
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pubmed:affiliation |
Department of Biochemistry, Medical School Hannover, Carl-Neuberg-Strasse 1, 30625 Hannover, Germany. gaestel.matthias@mh-hannover.de
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
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