rdf:type |
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lifeskim:mentions |
|
pubmed:issue |
3-4
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pubmed:dateCreated |
2006-1-19
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pubmed:abstractText |
The angiotensin converting enzyme (ACE) gene carries insertion (I) and deletion (D) polymorphism within its intron 16. The presence of D-allele in the ACE gene has been reported as a probable genetic risk factor for idiopathic nephrotic syndrome (INS), especially the subtype of focal segmental glomerulosclerosis (FSGS). The D-allele may be related to poor responsiveness to steroid therapy. To clarify the relationship between the D-allele and INS, we studied the prevalence of the D-allele in the Javanese-Indonesian patients. Additionally, we also analyzed relationship between each genotype and steroid sensitivity among the MCNS patients.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0023-2513
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
51
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
41-7
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pubmed:dateRevised |
2008-4-8
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pubmed:meshHeading |
pubmed-meshheading:16421456-Adolescent,
pubmed-meshheading:16421456-Alleles,
pubmed-meshheading:16421456-Asian Continental Ancestry Group,
pubmed-meshheading:16421456-Child,
pubmed-meshheading:16421456-Child, Preschool,
pubmed-meshheading:16421456-Female,
pubmed-meshheading:16421456-Genotype,
pubmed-meshheading:16421456-Glomerulosclerosis, Focal Segmental,
pubmed-meshheading:16421456-Humans,
pubmed-meshheading:16421456-Infant,
pubmed-meshheading:16421456-Male,
pubmed-meshheading:16421456-Nephrosis, Lipoid,
pubmed-meshheading:16421456-Peptidyl-Dipeptidase A,
pubmed-meshheading:16421456-Polymorphism, Genetic
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pubmed:year |
2005
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pubmed:articleTitle |
ACE gene polymorphism in children with nephrotic syndrome in the Indonesian population.
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pubmed:affiliation |
Division of Public Health, Kobe University Graduate School of Medicine. teguhharyosasongko@yahoo.com
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pubmed:publicationType |
Journal Article
|