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pubmed-article:16421365pubmed:abstractTextAbnormal homeostasis of the volume of airway surface liquid in patients with cystic fibrosis is thought to produce defects in mucus clearance and airway defense. Through osmotic forces, hypertonic saline may increase the volume of airway surface liquid, restore mucus clearance, and improve lung function.lld:pubmed
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pubmed-article:16421365pubmed:articleTitleMucus clearance and lung function in cystic fibrosis with hypertonic saline.lld:pubmed
pubmed-article:16421365pubmed:affiliationUniversity of North Carolina at Chapel Hill Cystic Fibrosis Research and Treatment Center, Chapel Hill 27599, USA. scott_donaldson@med.unc.edulld:pubmed
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