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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2006-1-19
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pubmed:abstractText |
Abnormal homeostasis of the volume of airway surface liquid in patients with cystic fibrosis is thought to produce defects in mucus clearance and airway defense. Through osmotic forces, hypertonic saline may increase the volume of airway surface liquid, restore mucus clearance, and improve lung function.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1533-4406
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2006 Massachusetts Medical Society.
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pubmed:issnType |
Electronic
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pubmed:day |
19
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pubmed:volume |
354
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
241-50
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:16421365-Administration, Inhalation,
pubmed-meshheading:16421365-Adolescent,
pubmed-meshheading:16421365-Adult,
pubmed-meshheading:16421365-Amiloride,
pubmed-meshheading:16421365-Biological Transport,
pubmed-meshheading:16421365-Cystic Fibrosis,
pubmed-meshheading:16421365-Female,
pubmed-meshheading:16421365-Forced Expiratory Volume,
pubmed-meshheading:16421365-Humans,
pubmed-meshheading:16421365-Male,
pubmed-meshheading:16421365-Maximal Midexpiratory Flow Rate,
pubmed-meshheading:16421365-Mucociliary Clearance,
pubmed-meshheading:16421365-Permeability,
pubmed-meshheading:16421365-Premedication,
pubmed-meshheading:16421365-Saline Solution, Hypertonic,
pubmed-meshheading:16421365-Sodium Channel Blockers,
pubmed-meshheading:16421365-Vital Capacity,
pubmed-meshheading:16421365-Water
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pubmed:year |
2006
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pubmed:articleTitle |
Mucus clearance and lung function in cystic fibrosis with hypertonic saline.
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pubmed:affiliation |
University of North Carolina at Chapel Hill Cystic Fibrosis Research and Treatment Center, Chapel Hill 27599, USA. scott_donaldson@med.unc.edu
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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