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rdf:type |
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lifeskim:mentions |
umls-concept:C0023434,
umls-concept:C0026882,
umls-concept:C0314603,
umls-concept:C0449438,
umls-concept:C0457083,
umls-concept:C0796349,
umls-concept:C0796366,
umls-concept:C1421567,
umls-concept:C1442161,
umls-concept:C1524062,
umls-concept:C1527940,
umls-concept:C1553586,
umls-concept:C1705831,
umls-concept:C1880022,
umls-concept:C2348519
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pubmed:issue |
6
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pubmed:dateCreated |
2006-2-17
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pubmed:abstractText |
Immunoglobulin heavy chain variable-region (VH) gene mutation status and zeta-associated protein 70 (ZAP-70) expression are correlated in chronic lymphocytic leukemia (CLL), but their concordance is variable. The goal of this study was to elucidate additional factors potentially characterizing their discordance.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1527-7755
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pubmed:author |
pubmed-author:BühlerAndreasA,
pubmed-author:BangerterMarkusM,
pubmed-author:BennerAxelA,
pubmed-author:BloehdornJohannesJ,
pubmed-author:DöhnerHartmutH,
pubmed-author:HafnerSebastianS,
pubmed-author:KienleDirkD,
pubmed-author:KröberAlexanderA,
pubmed-author:LichterPeterP,
pubmed-author:SchlenkRichard FRF,
pubmed-author:SeilerTillT,
pubmed-author:StilgenbauerStephanS,
pubmed-author:WinklerDirkD
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pubmed:issnType |
Electronic
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pubmed:day |
20
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
969-75
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:16418492-Chromosomes, Human, Pair 11,
pubmed-meshheading:16418492-Chromosomes, Human, Pair 17,
pubmed-meshheading:16418492-Flow Cytometry,
pubmed-meshheading:16418492-Gene Deletion,
pubmed-meshheading:16418492-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:16418492-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:16418492-Genetic Predisposition to Disease,
pubmed-meshheading:16418492-Humans,
pubmed-meshheading:16418492-Immunoglobulin Heavy Chains,
pubmed-meshheading:16418492-Immunoglobulin Variable Region,
pubmed-meshheading:16418492-In Situ Hybridization, Fluorescence,
pubmed-meshheading:16418492-Leukemia, Lymphocytic, Chronic, B-Cell,
pubmed-meshheading:16418492-Multivariate Analysis,
pubmed-meshheading:16418492-Mutation,
pubmed-meshheading:16418492-Predictive Value of Tests,
pubmed-meshheading:16418492-Prognosis,
pubmed-meshheading:16418492-Sequence Analysis, DNA,
pubmed-meshheading:16418492-Survival Analysis,
pubmed-meshheading:16418492-Tumor Markers, Biological,
pubmed-meshheading:16418492-ZAP-70 Protein-Tyrosine Kinase
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pubmed:year |
2006
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pubmed:articleTitle |
Additional genetic high-risk features such as 11q deletion, 17p deletion, and V3-21 usage characterize discordance of ZAP-70 and VH mutation status in chronic lymphocytic leukemia.
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pubmed:affiliation |
Department of Internal Medicine, University of Ulm, Ulm, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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