rdf:type |
|
lifeskim:mentions |
umls-concept:C0024880,
umls-concept:C0030685,
umls-concept:C0243043,
umls-concept:C0391871,
umls-concept:C0680255,
umls-concept:C1274040,
umls-concept:C1283071,
umls-concept:C1326120,
umls-concept:C1704259,
umls-concept:C1705987,
umls-concept:C1963578
|
pubmed:issue |
1
|
pubmed:dateCreated |
2006-1-17
|
pubmed:abstractText |
Mast cells are considered major players in IgE-mediated allergic responses, but have also recently been recognized as active participants in innate as well as specific immune responses. Heat stress can modulate innate immunity by inducing stress proteins such as heat shock proteins (HSPs). It has been reported that HSPs are capable of inducing the production of pro-inflammatory cytokines by the monocyte-macrophage system. In the current study, we explored whether the stress response induces HSPs and affects the signaling pathways of mast cells.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0301-472X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
34
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
8-18
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:16413386-Animals,
pubmed-meshheading:16413386-Arsenites,
pubmed-meshheading:16413386-Aspirin,
pubmed-meshheading:16413386-Autocrine Communication,
pubmed-meshheading:16413386-Cells, Cultured,
pubmed-meshheading:16413386-Cytokines,
pubmed-meshheading:16413386-HSP70 Heat-Shock Proteins,
pubmed-meshheading:16413386-Male,
pubmed-meshheading:16413386-Mast Cells,
pubmed-meshheading:16413386-Mice,
pubmed-meshheading:16413386-Mice, Inbred BALB C,
pubmed-meshheading:16413386-Mice, Inbred C3H,
pubmed-meshheading:16413386-Mice, Knockout,
pubmed-meshheading:16413386-Paracrine Communication,
pubmed-meshheading:16413386-Sodium Compounds,
pubmed-meshheading:16413386-Toll-Like Receptor 2,
pubmed-meshheading:16413386-Toll-Like Receptor 4
|
pubmed:year |
2006
|
pubmed:articleTitle |
Acetylsalicylic acid-induced release of HSP70 from mast cells results in cell activation through TLR pathway.
|
pubmed:affiliation |
Department of Pharmacology and Pathophysiology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.
|
pubmed:publicationType |
Journal Article,
Comparative Study
|