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rdf:type |
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lifeskim:mentions |
umls-concept:C0003483,
umls-concept:C0007452,
umls-concept:C0020456,
umls-concept:C0030685,
umls-concept:C0033268,
umls-concept:C0079281,
umls-concept:C0162772,
umls-concept:C0225336,
umls-concept:C0391871,
umls-concept:C0680255,
umls-concept:C0851827,
umls-concept:C1283071,
umls-concept:C1701901,
umls-concept:C1963578
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pubmed:issue |
2
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pubmed:dateCreated |
2006-2-15
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pubmed:abstractText |
Elevated plasma homocysteine (Hcy) is a risk factor for coronary disease. The objective of this study was to investigate whether Hcy either alone or in high glucose conditions induces endothelin-1 (ET-1) synthesis via the production of reactive oxygen species (ROS).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1018-1172
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
175-83
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:16410680-Animals,
pubmed-meshheading:16410680-Aorta,
pubmed-meshheading:16410680-Carbonyl Cyanide m-Chlorophenyl Hydrazone,
pubmed-meshheading:16410680-Cattle,
pubmed-meshheading:16410680-Cells, Cultured,
pubmed-meshheading:16410680-Electron Transport Complex II,
pubmed-meshheading:16410680-Endothelin-1,
pubmed-meshheading:16410680-Endothelium, Vascular,
pubmed-meshheading:16410680-Glucose,
pubmed-meshheading:16410680-Glutathione,
pubmed-meshheading:16410680-Homocysteine,
pubmed-meshheading:16410680-Hyperglycemia,
pubmed-meshheading:16410680-Oxidative Stress,
pubmed-meshheading:16410680-Reactive Oxygen Species,
pubmed-meshheading:16410680-Thenoyltrifluoroacetone,
pubmed-meshheading:16410680-Thromboplastin,
pubmed-meshheading:16410680-Uncoupling Agents
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pubmed:year |
2006
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pubmed:articleTitle |
Homocysteine-induced endothelin-1 release is dependent on hyperglycaemia and reactive oxygen species production in bovine aortic endothelial cells.
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pubmed:affiliation |
Department of Experimental Therapeutics, William Harvey Research Institute, London, UK. Amarjit.Sethi@eht.nhs.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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