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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
1992-8-31
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pubmed:abstractText |
Using the highly sensitive Polymerase chain reaction (PCR) hepatitis B virus (HBV) DNA has already been detected in many patients negative for all other serological HBV markers [12]. But yet, the relevance of these findings as a marker of infectivity has not been determined. We therefore have used the PCR to examine the perinatal route of HBV transmission by testing sera from 109 mother-child pairs in Yaoundé, Cameroon. HBV-DNA was detected in 25 (23%) of the mother's sera from which only 5 were positive for HBsAg. At the age of 6 months only one baby out of 25 who could be retested had become positive for HBV-DNA, HBsAg, and HBeAg. Low serum HBV-DNA levels which are still detectable by the PCR therefore seem not to be associated with a high risk of perinatal HBV transmission.
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pubmed:language |
ger
|
pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
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pubmed:issn |
0026-9298
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
140
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
366-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1640950-Carrier State,
pubmed-meshheading:1640950-DNA, Viral,
pubmed-meshheading:1640950-Developing Countries,
pubmed-meshheading:1640950-Female,
pubmed-meshheading:1640950-Hepatitis B,
pubmed-meshheading:1640950-Hepatitis B Surface Antigens,
pubmed-meshheading:1640950-Hepatitis B e Antigens,
pubmed-meshheading:1640950-Hepatitis B virus,
pubmed-meshheading:1640950-Humans,
pubmed-meshheading:1640950-Infant, Newborn,
pubmed-meshheading:1640950-Polymerase Chain Reaction,
pubmed-meshheading:1640950-Pregnancy,
pubmed-meshheading:1640950-Pregnancy Complications, Infectious,
pubmed-meshheading:1640950-Risk Factors
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pubmed:year |
1992
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pubmed:articleTitle |
[Perinatal hepatitis B virus transmission].
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pubmed:affiliation |
Universitäts-Kinderklinik, Giessen.
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pubmed:publicationType |
Journal Article,
English Abstract
|