Source:http://linkedlifedata.com/resource/pubmed/id/16407699
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2006-1-12
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pubmed:abstractText |
Angiotensin-converting enzyme (ACE) has two common genetic variants: the insertion (I) and deletion (D) forms. ACE levels are greater in subjects with the D allele, and several studies suggest superior endurance performance in subjects with the I allele. The authors recently reported the results of a 6-month exercise training protocol examining the effect of apolipoprotein E on the lipid response. The present report examines the relationship of ACE genotype and exercise adherence. DNA samples were available for 110 subjects: 14 I/I, 52 I/D, and 44 D/D. Baseline and change in maximal oxygen uptake, body mass index, skinfold thickness, and serum lipids did not differ by ACE genotype, but adherence to exercise training was higher in I carriers than in D homozygotes. These preliminary results suggest that ACE genotype affects exercise adherence and raises the possibility that superior endurance capacity in subjects with the I allele is related to a genetic propensity to adhere to an exercise regimen.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1520-037X
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pubmed:author |
pubmed-author:AngelopoulosTheodore JTJ,
pubmed-author:BilbieCherieC,
pubmed-author:GordonPaulP,
pubmed-author:MilesMaryM,
pubmed-author:MoynaNiallN,
pubmed-author:OrdovasJose MJM,
pubmed-author:PescatelloLindaL,
pubmed-author:SeipRichard LRL,
pubmed-author:ThompsonPaul DPD,
pubmed-author:TsongalisGregory JGJ,
pubmed-author:VisichPaulP,
pubmed-author:ZoellerRobertR
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pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
21-4
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pubmed:meshHeading |
pubmed-meshheading:16407699-Adolescent,
pubmed-meshheading:16407699-Adult,
pubmed-meshheading:16407699-Aged,
pubmed-meshheading:16407699-Alleles,
pubmed-meshheading:16407699-Apolipoproteins E,
pubmed-meshheading:16407699-Body Mass Index,
pubmed-meshheading:16407699-Exercise,
pubmed-meshheading:16407699-Exercise Tolerance,
pubmed-meshheading:16407699-Female,
pubmed-meshheading:16407699-Genotype,
pubmed-meshheading:16407699-Heart Rate,
pubmed-meshheading:16407699-Humans,
pubmed-meshheading:16407699-Male,
pubmed-meshheading:16407699-Middle Aged,
pubmed-meshheading:16407699-Oxygen Consumption,
pubmed-meshheading:16407699-Peptidyl-Dipeptidase A,
pubmed-meshheading:16407699-Physical Education and Training
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pubmed:year |
2006
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pubmed:articleTitle |
Angiotensin-converting enzyme genotype and adherence to aerobic exercise training.
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pubmed:affiliation |
Hartford Hospital, Hartford, CT 06102, USA. pthomps@harthosp.org
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pubmed:publicationType |
Journal Article
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