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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2006-1-12
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pubmed:abstractText |
The cycle of the photoactive yellow protein (PYP) has been extensively studied, but the dynamics of the isolated chromophore responsible for transduction is unknown. Here, we present real-time observation of the dynamics of the negatively charged chromophore and detection of intermediates along the path of trans-to-cis isomerization using femtosecond mass selection/electron detachment techniques. The results show that the role of the protein environment is not in the first step of double-bond twisting (barrier crossing) but in directing efficient conversion to the cis-structure and in impeding radical formation within the protein.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/16407155-10423446,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16407155-11352740,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16407155-12022854,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16407155-12718516,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16407155-12837088,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16407155-12939133,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16407155-15053611,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16407155-15146503,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16407155-15295641,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16407155-15345563,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16407155-15345564,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16407155-15884065,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16407155-16040745,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16407155-19431791,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16407155-2790139,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16407155-7756254,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16407155-7756529,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16407155-8491725,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16407155-9045611,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16407155-9515969
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0027-8424
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
10
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pubmed:volume |
103
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
258-62
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pubmed:dateRevised |
2010-9-21
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pubmed:meshHeading |
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pubmed:year |
2006
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pubmed:articleTitle |
Primary steps of the photoactive yellow protein: isolated chromophore dynamics and protein directed function.
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pubmed:affiliation |
Arthur Amos Noyes Laboratory of Chemical Physics, Laboratory for Molecular Sciences, California Institute of Technology, Pasadena, CA 91125, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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