rdf:type |
|
lifeskim:mentions |
umls-concept:C0006560,
umls-concept:C0010054,
umls-concept:C0021760,
umls-concept:C0021764,
umls-concept:C0027051,
umls-concept:C0030705,
umls-concept:C0032105,
umls-concept:C0086045,
umls-concept:C0205156,
umls-concept:C0205250,
umls-concept:C0439793,
umls-concept:C0439849,
umls-concept:C0445223,
umls-concept:C1552599,
umls-concept:C1704787
|
pubmed:issue |
2
|
pubmed:dateCreated |
2006-9-4
|
pubmed:abstractText |
Interleukin-18 (IL-18) is a pro-inflammatory cytokine with a central role in the inflammatory cascade. In the present study, we investigated whether patients with precocious myocardial infarction have higher plasma IL-18 concentrations than matched controls. Furthermore, the relationships between plasma IL-18 concentrations and coronary atherosclerosis, C-reactive protein (CRP), interleukin-6 (IL-6) and traditional cardiovascular risk factors were examined.
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0021-9150
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
188
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
450-4
|
pubmed:dateRevised |
2011-11-17
|
pubmed:meshHeading |
pubmed-meshheading:16405895-Age Factors,
pubmed-meshheading:16405895-Blood Pressure,
pubmed-meshheading:16405895-Body Mass Index,
pubmed-meshheading:16405895-C-Reactive Protein,
pubmed-meshheading:16405895-Cholesterol,
pubmed-meshheading:16405895-Coronary Angiography,
pubmed-meshheading:16405895-Coronary Artery Disease,
pubmed-meshheading:16405895-Female,
pubmed-meshheading:16405895-Humans,
pubmed-meshheading:16405895-Insulin,
pubmed-meshheading:16405895-Interleukin-18,
pubmed-meshheading:16405895-Interleukin-6,
pubmed-meshheading:16405895-Male,
pubmed-meshheading:16405895-Middle Aged,
pubmed-meshheading:16405895-Myocardial Infarction,
pubmed-meshheading:16405895-Nephelometry and Turbidimetry,
pubmed-meshheading:16405895-Risk Factors,
pubmed-meshheading:16405895-Sweden
|
pubmed:year |
2006
|
pubmed:articleTitle |
Plasma interleukin (IL)-18 concentrations is elevated in patients with previous myocardial infarction and related to severity of coronary atherosclerosis independently of C-reactive protein and IL-6.
|
pubmed:affiliation |
Discovery Medicine, AstraZeneca, Mölndal, Sweden; Wallenberg Laboratory for Cardiovascular Research, Sahlgrenska University Hospital, Gothenburg, Sweden. Johannes.Hulthe@astrazeneca.com
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|