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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2 Pt 2
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pubmed:dateCreated |
1992-8-31
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pubmed:abstractText |
The clinical course of 138 children who underwent unilateral nephrectomy and had a normal contralateral kidney at the time of nephrectomy was reviewed. The diagnosis leading to nephrectomy included obstructive uropathy in 46% of the cases, reflux or pyelonephritis in 30%, Wilms tumor in 15%, hypertension in 4%, dysplastic kidney in 2% and trauma in 2%. Mean age at nephrectomy was 7.3 years and median followup was 24.7 years. Of the 138 patients 121 (88%) are well and 17 died, including 14 secondary to metastatic Wilms tumor and 1 of renal failure. Survival of nonWilms tumor patients was similar to that of an age-matched control group. In 30 patients 24-hour creatinine clearance and 24-hour urinary protein excretion were measured. Proteinuria (greater than 150 mg./24 hours) was found in 8 of the 30 patients (27%) (p less than 0.001), renal insufficiency developed in 9 (30%) (p less than 0.0001) and hypertension occurred in 10% (p greater than 0.10). Children with an acquired solitary kidney are at increased risk for proteinuria and renal insufficiency.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0022-5347
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
148
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
747-51
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1640559-Child,
pubmed-meshheading:1640559-Female,
pubmed-meshheading:1640559-Humans,
pubmed-meshheading:1640559-Hypertension, Renal,
pubmed-meshheading:1640559-Kidney,
pubmed-meshheading:1640559-Kidney Failure, Chronic,
pubmed-meshheading:1640559-Kidney Function Tests,
pubmed-meshheading:1640559-Male,
pubmed-meshheading:1640559-Nephrectomy,
pubmed-meshheading:1640559-Prognosis,
pubmed-meshheading:1640559-Proteinuria
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pubmed:year |
1992
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pubmed:articleTitle |
Prognosis of children with solitary kidney after unilateral nephrectomy.
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pubmed:affiliation |
Department of Urology, Mayo Clinic, Rochester, Minnesota 55905.
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pubmed:publicationType |
Journal Article
|