Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1992-8-31
pubmed:abstractText
The effect of prostaglandin F2 alpha (PGF2 alpha) on calcium efflux from ciliary smooth muscle cells was studied. Ciliary smooth muscle cells, cultured from human ciliary muscle explants, retained the morphologic and immunologic characteristics of smooth muscle cells. High concentrations (to 10(-6) mol/l) of PGF2 alpha were associated with a dose-dependent increase of calcium (45Ca) efflux, whereas at concentrations lower than 10(-8) mol/l there was little or no 45Ca efflux. Our in vitro data are inconsistent with the experimental hypothesis that PGF2 alpha at pharmacologic concentrations relaxes ciliary muscle with a consequent increase in uveoscleral outflow.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0146-0404
pubmed:author
pubmed:issnType
Print
pubmed:volume
33
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2679-86
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Propagation of ciliary smooth muscle cells in vitro and effects of prostaglandin F2 alpha on calcium efflux.
pubmed:affiliation
Department of Ophthalmology, University of California, San Diego.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.