Source:http://linkedlifedata.com/resource/pubmed/id/16392026
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2006-3-23
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pubmed:abstractText |
Raloxifene improves spine bone mineral density (BMD), and its ability to reduce vertebral fractures by 40-50% suggests that it increases vertebral strength. Positive effects on hip BMD suggest a similar strengthening of the hip, but dimensional ambiguities in BMD by dual energy x-ray absorptiometry (DXA) make it difficult to infer strength effects directly. Hip fractures may be too infrequent to evaluate in practical clinical trials; even the Multiple Outcomes of Raloxifene Evaluation (MORE) study with 7,705 subjects was insufficiently powered to show a comparable reduction in hip fractures.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0937-941X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
575-86
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:16392026-Absorptiometry, Photon,
pubmed-meshheading:16392026-Aged,
pubmed-meshheading:16392026-Bone Density,
pubmed-meshheading:16392026-Bone Density Conservation Agents,
pubmed-meshheading:16392026-Female,
pubmed-meshheading:16392026-Hip,
pubmed-meshheading:16392026-Humans,
pubmed-meshheading:16392026-Osteoporosis, Postmenopausal,
pubmed-meshheading:16392026-Prospective Studies,
pubmed-meshheading:16392026-Raloxifene,
pubmed-meshheading:16392026-Treatment Outcome
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pubmed:year |
2006
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pubmed:articleTitle |
Structural effects of raloxifene on the proximal femur: results from the multiple outcomes of raloxifene evaluation trial.
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pubmed:affiliation |
Department of Radiology, The Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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