Source:http://linkedlifedata.com/resource/pubmed/id/16391194
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2006-1-4
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pubmed:abstractText |
Locoregional (LR) administration of (90)Y-conjugates after surgical debulking is a promising therapeutic option of gliomas. Dosimetry is highly recommended, as patient-specific parameters influence the absorbed dose to target and normal tissues. After tumor resection, the absorbed dose must be carefully evaluated in the rim of tissue surrounding the resected area. The aim of this study was to calculate and provide the S values, according to the MIRD concept, for dosimetry of LR brain treatments with several (90)Y-labeled compounds. The S values thus obtained have been clinically applied in 12 patients treated with (90)Y-labeled [DOTA(0),D-Phe(1),Tyr(3)]octreotide ((90)Y-DOTATOC).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0161-5505
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
105-12
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pubmed:meshHeading |
pubmed-meshheading:16391194-Adult,
pubmed-meshheading:16391194-Aged,
pubmed-meshheading:16391194-Brain Neoplasms,
pubmed-meshheading:16391194-Computer Simulation,
pubmed-meshheading:16391194-Female,
pubmed-meshheading:16391194-Humans,
pubmed-meshheading:16391194-Injections, Intralesional,
pubmed-meshheading:16391194-Male,
pubmed-meshheading:16391194-Middle Aged,
pubmed-meshheading:16391194-Models, Biological,
pubmed-meshheading:16391194-Octreotide,
pubmed-meshheading:16391194-Radiometry,
pubmed-meshheading:16391194-Radiopharmaceuticals,
pubmed-meshheading:16391194-Radiotherapy, Computer-Assisted,
pubmed-meshheading:16391194-Radiotherapy Dosage,
pubmed-meshheading:16391194-Radiotherapy Planning, Computer-Assisted,
pubmed-meshheading:16391194-Relative Biological Effectiveness
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pubmed:year |
2006
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pubmed:articleTitle |
Dosimetric model for locoregional treatments of brain tumors with 90Y-conjugates: clinical application with 90Y-DOTATOC.
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pubmed:affiliation |
Division of Nuclear Medicine, European Institute of Oncology, Milan, Italy.
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pubmed:publicationType |
Journal Article,
Clinical Trial
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