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rdf:type |
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lifeskim:mentions |
umls-concept:C0031090,
umls-concept:C0079189,
umls-concept:C0085488,
umls-concept:C0205263,
umls-concept:C0205463,
umls-concept:C0243077,
umls-concept:C0449258,
umls-concept:C0449774,
umls-concept:C0623362,
umls-concept:C0919336,
umls-concept:C1367028,
umls-concept:C1517004,
umls-concept:C1709059
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pubmed:issue |
1
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pubmed:dateCreated |
2006-1-4
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pubmed:abstractText |
Inflammatory and immune reactions raised in response to periodontopathogens are thought to trigger periodontal tissue destruction. We therefore investigated the expression of matrix metalloproteinases (MMPs) and the osteoclastogenic factor RANKL (receptor activator of nuclear factor-kappaB ligand), their respective inhibitors TIMPs (tissue inhibitors of metalloproteinases) and OPG (osteoprotegerin) and their possible correlation with the expression of inflammatory and regulatory cytokines in the course of experimental periodontal disease in mice.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
D
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Cathepsin K,
http://linkedlifedata.com/resource/pubmed/chemical/Cathepsins,
http://linkedlifedata.com/resource/pubmed/chemical/Ctsk protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Cysteine Endopeptidases,
http://linkedlifedata.com/resource/pubmed/chemical/Cytokines,
http://linkedlifedata.com/resource/pubmed/chemical/Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Interferon-gamma,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukins,
http://linkedlifedata.com/resource/pubmed/chemical/Ligands,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinases,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Osteoprotegerin,
http://linkedlifedata.com/resource/pubmed/chemical/RANK Ligand,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor Activator of Nuclear...,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cytoplasmic and Nuclear,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Tumor Necrosis Factor,
http://linkedlifedata.com/resource/pubmed/chemical/Tissue Inhibitor of...,
http://linkedlifedata.com/resource/pubmed/chemical/Tnfrsf11a protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Tnfrsf11b protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Tnfsf11 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor...,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0902-0055
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
12-20
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:16390336-Actinobacillus Infections,
pubmed-meshheading:16390336-Actinobacillus actinomycetemcomitans,
pubmed-meshheading:16390336-Alveolar Bone Loss,
pubmed-meshheading:16390336-Animals,
pubmed-meshheading:16390336-Carrier Proteins,
pubmed-meshheading:16390336-Cathepsin K,
pubmed-meshheading:16390336-Cathepsins,
pubmed-meshheading:16390336-Cell Movement,
pubmed-meshheading:16390336-Cysteine Endopeptidases,
pubmed-meshheading:16390336-Cytokines,
pubmed-meshheading:16390336-Disease Progression,
pubmed-meshheading:16390336-Glycoproteins,
pubmed-meshheading:16390336-Interferon-gamma,
pubmed-meshheading:16390336-Interleukins,
pubmed-meshheading:16390336-Leukocytes,
pubmed-meshheading:16390336-Ligands,
pubmed-meshheading:16390336-Male,
pubmed-meshheading:16390336-Matrix Metalloproteinases,
pubmed-meshheading:16390336-Membrane Glycoproteins,
pubmed-meshheading:16390336-Mice,
pubmed-meshheading:16390336-Mice, Inbred C57BL,
pubmed-meshheading:16390336-Osteoprotegerin,
pubmed-meshheading:16390336-Periodontal Diseases,
pubmed-meshheading:16390336-RANK Ligand,
pubmed-meshheading:16390336-Receptor Activator of Nuclear Factor-kappa B,
pubmed-meshheading:16390336-Receptors, Cytoplasmic and Nuclear,
pubmed-meshheading:16390336-Receptors, Tumor Necrosis Factor,
pubmed-meshheading:16390336-Tissue Inhibitor of Metalloproteinases,
pubmed-meshheading:16390336-Tumor Necrosis Factor Receptor-Associated Peptides and...,
pubmed-meshheading:16390336-Tumor Necrosis Factor-alpha
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pubmed:year |
2006
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pubmed:articleTitle |
Cytokine pattern determines the progression of experimental periodontal disease induced by Actinobacillus actinomycetemcomitans through the modulation of MMPs, RANKL, and their physiological inhibitors.
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pubmed:affiliation |
Department of Biochemistry and Immunology, School of Medicine-USP, Ribeirao Preto, SP, Brazil. gustavo@rpm.fmrp.usp.br
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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