Source:http://linkedlifedata.com/resource/pubmed/id/16388385
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2006-1-2
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pubmed:abstractText |
A new class of materials based on inorganic and organic species combined at a nanoscale level has received large attention recently. In this work the idea of producing hybrid materials with controllable properties is applied to obtain foams to be used as scaffolds for tissue engineering. Hybrids were synthesized by reacting poly(vinyl alcohol) in acidic solution with tetraethylorthosilicate. The inorganic phase was also modified by incorporating a calcium compound. Hydrated calcium chloride was used as precursor. A surfactant was added and a foam was produced by vigorous agitation, which was cast just before the gel point. Hydrofluoric acid solution was added in order to catalyze the gelation. The foamed hybrids were aged at 40 degrees C and vacuum dried at 40 degrees C. The hybrid foams were analyzed by Scanning Electron Microscopy, Mercury Porosimetry, Nitrogen Adsorption, X-ray Diffraction and Infra-red Spectroscopy. The mechanical behavior was evaluated by compression tests. The foams obtained had a high porosity varying from 60 to 90% and the macropore diameter ranged from 30 to 500 microm. The modal macropore diameter varied with the inorganic phase composition and with the polymer content in the hybrid. The surface area and mesopore volume decreased as polymer concentration increased in the hybrids. The strain at fracture of the hybrid foams was substantially greater than pure gel-glass foams.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0957-4530
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1045-50
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16388385-Biocompatible Materials,
pubmed-meshheading:16388385-Gels,
pubmed-meshheading:16388385-Glass,
pubmed-meshheading:16388385-Microscopy, Electron, Scanning,
pubmed-meshheading:16388385-Polymers,
pubmed-meshheading:16388385-Polyvinyl Alcohol,
pubmed-meshheading:16388385-Tissue Engineering
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pubmed:year |
2005
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pubmed:articleTitle |
Preparation of bioactive glass-polyvinyl alcohol hybrid foams by the sol-gel method.
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pubmed:affiliation |
Department of Materials, Imperial College London, UK. mpereira@demet.ufmg.br
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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