Linked Life Data

16386965

Source:http://linkedlifedata.com/resource/pubmed/id/16386965

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2006-8-29
pubmed:abstractText
Nano titanium dioxide (TiO2) and hemoglobin (Hb) were co-modified on pyrolytic graphite (PG) electrode to study the photovoltaic effect of TiO2 nanoparticles (NPs) on the electron transfer reactivity and catalytic activity of the protein. By means of cyclic voltammetry (CV) and FTIR measurements, the study was characterized in both aerobic and anaerobic environments. Experimental results revealed that the factors which mainly interacted with Hb were electron/hole pairs and reactive oxygen species (ROS) generated by the photovoltaic effect when TiO2 NPs were irradiated under ultraviolet (UV) light. The electron/hole pairs generated on the surface of TiO2 would influence the structure of Hb gently, so the electron transfer reactivity and catalytic ability of the protein slightly changed. In contrast, ROS interacted with Hb intensively, which brought in much conformational change to Hb and its active centers, and even cause some damage. Consequently, the electron transfer reactivity and catalytic activity of Hb changed with a process of increasing initially and decreasing afterwards.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1567-5394
pubmed:author
pubmed:issnType
Print
pubmed:volume
69
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
34-40
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Electrochemical study of photovoltaic effect of nano titanium dioxide on hemoglobin.
pubmed:affiliation
Department of Biochemistry and National Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, P. R. China.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't