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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2005-12-30
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pubmed:abstractText |
Age-related macular degeneration (AMD) is a retinal degenerative disease that is the leading cause of blindness worldwide for individuals over the age of 60. Although the etiology of AMD remains largely unknown, numerous studies have suggested that both genes and environmental risk factors significantly influence the risk of developing AMD. Identification of the underlying genes has been difficult, with both genomic screen (locational) and candidate gene (functional) approaches being used. The present study tested candidate genes for association with AMD.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Creatine Kinase,
http://linkedlifedata.com/resource/pubmed/chemical/Glutathione Transferase,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-1,
http://linkedlifedata.com/resource/pubmed/chemical/LRP6 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Low Density Lipoprotein...,
http://linkedlifedata.com/resource/pubmed/chemical/Peptidyl-Dipeptidase A,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, LDL,
http://linkedlifedata.com/resource/pubmed/chemical/VEGFA protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/VLDL receptor,
http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factor A,
http://linkedlifedata.com/resource/pubmed/chemical/alpha-Macroglobulins
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0146-0404
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pubmed:author |
pubmed-author:AgarwalAnitaA,
pubmed-author:GilbertJohn RJR,
pubmed-author:HainesJonathan LJL,
pubmed-author:HauserMichaelM,
pubmed-author:KenealyShannon JSJ,
pubmed-author:OlsonLanaL,
pubmed-author:Pericak-VanceMargaret AMA,
pubmed-author:PostelEric AEA,
pubmed-author:SchmidtSilkeS,
pubmed-author:Schnetz-BoutaudNathalieN,
pubmed-author:ScottWilliam KWK
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pubmed:issnType |
Print
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
329-35
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:16384981-Aged,
pubmed-meshheading:16384981-Case-Control Studies,
pubmed-meshheading:16384981-Creatine Kinase,
pubmed-meshheading:16384981-Female,
pubmed-meshheading:16384981-Genetic Linkage,
pubmed-meshheading:16384981-Genotype,
pubmed-meshheading:16384981-Glutathione Transferase,
pubmed-meshheading:16384981-Humans,
pubmed-meshheading:16384981-Interleukin-1,
pubmed-meshheading:16384981-Low Density Lipoprotein Receptor-Related Protein-6,
pubmed-meshheading:16384981-Macular Degeneration,
pubmed-meshheading:16384981-Male,
pubmed-meshheading:16384981-Pedigree,
pubmed-meshheading:16384981-Peptidyl-Dipeptidase A,
pubmed-meshheading:16384981-Polymorphism, Single Nucleotide,
pubmed-meshheading:16384981-Receptors, LDL,
pubmed-meshheading:16384981-Risk Factors,
pubmed-meshheading:16384981-Vascular Endothelial Growth Factor A,
pubmed-meshheading:16384981-alpha-Macroglobulins
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pubmed:year |
2006
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pubmed:articleTitle |
Functional candidate genes in age-related macular degeneration: significant association with VEGF, VLDLR, and LRP6.
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pubmed:affiliation |
Center for Human Genetics Research, Vanderbilt University Medical Center, Nashville, TN 37232, USA. jonathan@chgr.mc.vanderbilt.edu
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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