rdf:type |
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lifeskim:mentions |
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pubmed:issue |
Database issue
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pubmed:dateCreated |
2005-12-29
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pubmed:abstractText |
The completion of the sequencing of the human genome and the concurrent, rapid development of high-throughput proteomic methods have resulted in an increasing need for automated approaches to archive proteomic data in a repository that enables the exchange of data among researchers and also accurate integration with genomic data. PeptideAtlas (http://www.peptideatlas.org/) addresses these needs by identifying peptides by tandem mass spectrometry (MS/MS), statistically validating those identifications and then mapping identified sequences to the genomes of eukaryotic organisms. A meaningful comparison of data across different experiments generated by different groups using different types of instruments is enabled by the implementation of a uniform analytic process. This uniform statistical validation ensures a consistent and high-quality set of peptide and protein identifications. The raw data from many diverse proteomic experiments are made available in the associated PeptideAtlas repository in several formats. Here we present a summary of our process and details about the Human, Drosophila and Yeast PeptideAtlas builds.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
1362-4962
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
D655-8
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:16381952-Animals,
pubmed-meshheading:16381952-Chromosome Mapping,
pubmed-meshheading:16381952-Databases, Protein,
pubmed-meshheading:16381952-Drosophila Proteins,
pubmed-meshheading:16381952-Humans,
pubmed-meshheading:16381952-Internet,
pubmed-meshheading:16381952-Mass Spectrometry,
pubmed-meshheading:16381952-Peptide Fragments,
pubmed-meshheading:16381952-Proteome,
pubmed-meshheading:16381952-Proteomics,
pubmed-meshheading:16381952-Saccharomyces cerevisiae Proteins,
pubmed-meshheading:16381952-Sequence Analysis, Protein,
pubmed-meshheading:16381952-User-Computer Interface
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pubmed:year |
2006
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pubmed:articleTitle |
The PeptideAtlas project.
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pubmed:affiliation |
Institute for Systems Biology, Seattle, WA, USA. fdesiere@yahoo.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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