Linked Life Data

16378474

Source:http://linkedlifedata.com/resource/pubmed/id/16378474

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2005-12-27
pubmed:abstractText
This study of 4,274 pairs of 4-year-old twins from the Twins Early Development Study explored the magnitude of genetic and environmental effects on low expressive vocabulary skill, both as a function of general cognitive ability and as a function of the severity of expressive vocabulary impairment. Assessments were conducted through parent report measures. Two types of vocabulary deficit were identified: low vocabulary paired with typical general cognition (i.e., specific expressive vocabulary impairment) and low vocabulary paired with low general cognition (i.e., nonspecific expressive vocabulary impairment). The magnitude of genetic and environmental effects on low expressive vocabulary skill did not differ for these 2 types of expressive vocabulary deficit. By systematically varying the cutoffs used to define vocabulary and general cognitive delay, potential changes in the magnitude of genetic and environmental effects were examined. Results suggested that the severity of vocabulary deficit rather than level of cognitive functioning was a more meaningful etiological distinction: The heritability of low expressive vocabulary was higher and the influence of shared environment lower, as increasingly severe vocabulary deficits were identified. Implications for molecular genetics and the construct of specific language deficits are discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1092-4388
pubmed:author
pubmed:issnType
Print
pubmed:volume
48
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
792-804
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Low expressive vocabulary: higher heritability as a function of more severe cases.
pubmed:affiliation
Pennsylvania State University, University Park, USA. lauras@uiuc.edu
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't