Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2005-12-26
pubmed:abstractText
The interaction of dietary protein type and fat level on the body fat-reducing activity of conjugated linoleic acid (CLA) was studied in male rats fed diets containing casein (CAS) or soy protein (SOY) as a protein source with low fat (LF, 6.0% soybean oil) or high fat (HF, 13.0% soybean oil) combinations for 4 weeks. CLA was added at the 1.0% level to all diets. The weight of perirenal adipose tissue tended to be lower in the SOY groups than in the corresponding CAS groups, and the difference between the LF diets was significant. The weight of epididymal adipose tissue showed a similar but insignificant trend. The weight of brown adipose tissue was heaviest on the SOY-HF diet and lowest on two CAS diets, the SOY-LF diet being intermediate. The concentration of serum leptin was lowest on the SOY-LF diet and was significantly lower than that of the corresponding CAS group, but this difference disappeared when the dietary fat level increased. The serum cholesterol-lowering activity of SOY in relation to CAS was reproduced even when CLA was given. Thus the body fat-reducing activity of CLA was most marked when rats were fed the SOY-LF diet. Although the CAS-HF diet increased body fat deposition, the magnitude of the reduction by lowering dietary fat level was more marked than in the case of SOY. These results indicate a complicated interaction of dietary manipulations with the body fat-reducing effect of CLA, but the combination of CLA with the SOY-LF diet appears to be an appropriate approach.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0916-8451
pubmed:author
pubmed:issnType
Print
pubmed:volume
69
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2409-15
pubmed:meshHeading
pubmed-meshheading:16377901-Adipose Tissue, pubmed-meshheading:16377901-Animals, pubmed-meshheading:16377901-Anti-Obesity Agents, pubmed-meshheading:16377901-Body Weight, pubmed-meshheading:16377901-Caseins, pubmed-meshheading:16377901-Cytokines, pubmed-meshheading:16377901-Diet, pubmed-meshheading:16377901-Dietary Fats, pubmed-meshheading:16377901-Dietary Proteins, pubmed-meshheading:16377901-Epididymis, pubmed-meshheading:16377901-Fatty Acids, pubmed-meshheading:16377901-Leptin, pubmed-meshheading:16377901-Linoleic Acid, pubmed-meshheading:16377901-Lipid Metabolism, pubmed-meshheading:16377901-Lipids, pubmed-meshheading:16377901-Liver, pubmed-meshheading:16377901-Male, pubmed-meshheading:16377901-Organ Size, pubmed-meshheading:16377901-Oxidation-Reduction, pubmed-meshheading:16377901-Rats, pubmed-meshheading:16377901-Rats, Sprague-Dawley, pubmed-meshheading:16377901-Soybean Proteins, pubmed-meshheading:16377901-Weight Gain
pubmed:year
2005
pubmed:articleTitle
Combined effects of dietary protein type and fat level on the body fat-reducing activity of conjugated linoleic acid (CLA) in rats.
pubmed:affiliation
Faculty of Environmental and Symbiotic Sciences, Prefectural University of Kumamoto, Japan. a-asuka@pu.kumamoto.ac.jp
pubmed:publicationType
Journal Article