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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2005-12-23
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pubmed:abstractText |
G protein-coupled receptors may up-regulate the inflammatory response elicited by ventilator-induced lung injury but also regulate cell survival via protein kinase B (Akt) and extracellular signal regulated kinases 1/2 (ERK1/2). The G protein-sensitive phosphoinositide-3-kinase gamma (PI3Kgamma) regulates several cellular functions including inflammation and cell survival. We explored the role of PI3Kgamma on ventilator-induced lung injury.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0090-3493
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pubmed:author |
pubmed-author:CeciSimoneS,
pubmed-author:De GiuliPaoloP,
pubmed-author:FanelliVitoV,
pubmed-author:GremigniVittorioV,
pubmed-author:HirschEmilioE,
pubmed-author:LenaAnnalisaA,
pubmed-author:LionettiVincenzoV,
pubmed-author:LisiAlbertoA,
pubmed-author:MilazzoMaria GiovannaMG,
pubmed-author:PatruccoEnricoE,
pubmed-author:RanieriV MarcoVM,
pubmed-author:WymannMatthiasM
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pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
134-41
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:16374167-Animals,
pubmed-meshheading:16374167-Biological Markers,
pubmed-meshheading:16374167-Biopsy, Needle,
pubmed-meshheading:16374167-Cytokines,
pubmed-meshheading:16374167-Disease Models, Animal,
pubmed-meshheading:16374167-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:16374167-Immunohistochemistry,
pubmed-meshheading:16374167-Lung,
pubmed-meshheading:16374167-Lung Diseases,
pubmed-meshheading:16374167-Lung Injury,
pubmed-meshheading:16374167-Male,
pubmed-meshheading:16374167-Mice,
pubmed-meshheading:16374167-Mice, Knockout,
pubmed-meshheading:16374167-Phosphatidylinositol 3-Kinases,
pubmed-meshheading:16374167-Random Allocation,
pubmed-meshheading:16374167-Reference Values,
pubmed-meshheading:16374167-Respiration, Artificial,
pubmed-meshheading:16374167-Respiratory Function Tests,
pubmed-meshheading:16374167-Respiratory Insufficiency,
pubmed-meshheading:16374167-Sensitivity and Specificity,
pubmed-meshheading:16374167-Up-Regulation
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pubmed:year |
2006
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pubmed:articleTitle |
Lack of phosphoinositide 3-kinase-gamma attenuates ventilator-induced lung injury.
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pubmed:affiliation |
Dipartimento di Anestesiologia e Rianimazione, Ospedale S. Giovanni Battista-Molinette, Università di Torino, Torino, Italy.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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